Laura, a 2002-2006 Self Fellow, received her Ph.D. in pharmaceutical
chemistry in 2006. She received a B.S. (2002) in chemistry and a minor
in mathematics summa cum laude from Baker University. Laura's KU
research focused on developing a systematic approach to preformulation
development, specifically of recombinant protein vaccine candidates. The
goals was for this three-step approach to more thorough, faster, and
much less wasteful of the recombinant protein. She also worked to
develop a library of GRAS (Generally Regarded as Safe) compounds to
compile a thorough, successful library to rapidly screen for stabilizers
of all recombinant protein vaccine candidates. Although this approach
was being developed for vaccines, it also should be useful for the
development of other classes of protein-based pharmaceuticals. Getting
drugs to the market faster will benefit all of society by making them
available sooner to those individuals who would benefit from their use.
At KU Laura applied this approach to vaccine candidates for malaria,
anthrax and ricin. She also studied changes that occur in protein
structure when adsorbed to aluminum salt adjuvants.
Laura is currently a Senior Scientist at Oncimmune US in Lenexa, Kansas.
Mentor: Charles R. Middaugh, Distinguished Professor, Pharmaceutical
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