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News
Recent Molecular Biosciences doctoral graduate Dr. Natasha DeVore (Spring, 2011) had a portion of her dissertation research published as an article in the journal Nature. Natasha did her dissertation work with Molecular Biosciences affiliate faculty member Dr. Emily Scott (associate professor, Medicinal Chemistry). Read about their article here: http://www.news.ku.edu/2012/
january/24/cancerenzyme.shtml
Presentations
Berl Oakley (professor) gave a presentation entitled "Accessing the fungal secondary metabolome to improve human health" in the Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University School of Medicine, Columbus, Ohio on January 11. He also gave a presentation entitled "Accessing the fungal secondary metabolome—a rich source of medically important compounds" in the Department of Plant Pathology, Kansas State University, Manhattan, Kansas on January 19.
Current Publications
February
Devore NM and Scott EE. Structures of cyctochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001. Nature 2012 Jan 22 [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22266943
Estrada DF, Conner M, Joer SC and De Guzman RN. The structure of the hantavirus zinc finger domain is conserved and represents the only natively folded region of the Gn cytoplasmic tail. Front Microbiol 2:251.
http://www.ncbi.nlm.nih.gov/pubmed/22203819
Lian J, Ni Z, Dai X, Su C, Smith AR and Xu L, and He F. Sorafenib sensitizes (-)-gossypol-induced growth suppression in androgen-independent prostate cancer cells via Mcl-1 inhibition and Bak activation. Molecular Cancer Therapeutics 2011, Dec. in press
http://www.ncbi.nlm.nih.gov/pubmed/22188816
Marquez RT and Xu L. Bcl2:Beclin 1 complex: multiple mechanisms regulating autophagy/apoptosis toggle switch. Am J Cancer Res 2012;2(2). (in press)
http://www.ajcr.us/ajcr0000098A.html
Simeone DM, Ljungman M, Xu L, Wang L and He F. Compositions and methods for treating cancer. US Patent No. US 8,088749, issued on Jan. 3, 2012.
Voss K, Combs B, Patterson KR, Binder LI and Gamblin TC. Hsp70 alters tau function and aggregation in an isoform specific manner. Biochemistry 2012 Jan 10 [Epub ahead of print]
http://www.ncbi.nlm.nih.gov/pubmed/22236337