PATH 806: Epigenetics (2)

Current concepts in epigenetic regulation of transcription, including its involvement in disease. Current scientific literature will be used to examine recent advances in the role of epigenetic regulation in transcription and its impact on cellular processes, including growth, differentiation, development, and disease. Students will learn the fundamental concepts of epigenetic regulation and the role of the epigenetic regulation in various gene expression systems. The role of epigenetics in long-range DNA interactions will also be studied, with an emphasis on enhancer, silencer, and locus control region function. Recent advances in the role of epigenetics in disease, including cancer will also be examine. The course will examine current experimental methods to study epigenetics and gene regulation. Prerequisite: Completion of the IGPBS core curriculum or equivalent; consent of instructor. LEC
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