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Department of Pharmacology and Toxicology

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Research facilities offer a range of modern instrumentation and many research support services. Major instruments include tissue culture rooms, ultra-centrifuges, flow cytometry, scintillation counters, high-pressure liquid chromatography systems, computer-driven fluorometers and spectrophotometers, and light and fluorescence microscopy systems. Several laboratory groups have more specialized equipment for molecular biology, protein purification and analysis, electrophysiology and calcium imaging, immunochemistry, and related techniques. All labs have current computer technology, including hardware and extensive software for imaging, data analysis, data reduction, protein and gene analysis, and statistical tests.

Specialized research support labs include a confocal and an electron microscopy laboratory with both transmission and scanning scopes; a transgenic and knockout mouse facility; a gene-chip and microarray facility; a Biochemical Research Service Laboratory with DNA sequencing, DNA microarrays, peptide synthesis, fermentation, and MALDI-TOF instrumentation; a Molecular Graphics and Modeling Laboratory with extensive data bases for protein structures; an NMR facility; an X-ray Crystallography Laboratory; a Mass Spectrometry Laboratory; and an Instrumentation Design Laboratory.

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