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Department of Pharmaceutical Chemistry

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The department is on KU’s west campus in Simons Biosciences Research Laboratories, a 30,000-square-foot, 2-story research facility completed in 1996. There are 18 general laboratories and an experimental cancer chemotherapeutic-agent testing laboratory, a radioisotope handling room, a molecular biology laboratory, a natural products extraction laboratory, and a liquid chromatography mass spectrometry laboratory. The laboratories contain an extensive array of equipment and instrumentation. The department currently maintains 5 mass spectrometers. There are facilities for cell culture, several advanced fluorescence microscopes, NMRs (both solution state and solid state), and numerous components and software for proteomic analysis. In addition, an extensive array of instrumentation is available for the characterization of both small and macromolecules including a circular dichroism spectrophotometer, FTIR, and light-scattering instrumentation to name a few.

An amazing array of equipment and service facilities help with nearly any aspect of research. For example, the Molecular Structures Group is a campuswide facility encompassing NMR, MS, X-ray Crystallography, Biochemical Research Service, and Molecular Graphics and Modeling Laboratories available to all campus members for a nominal fee. Near the Simons building, the structural biology wing of the MSG houses an 800-mHz NMR along with many other instruments and services. The recently completed Multidisciplinary Research Building houses researchers from a variety of disciplines to encourage interaction and collaboration. Professors Middaugh, Lunte, Berkland, and Laurence occupy space in this new facility.

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