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Department of Pharmaceutical Chemistry

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Principal Course Distribution Requirement

Principal courses offer introductions to the breadth of disciplines in the College. They acquaint students with the subject matter in an area, with the types of questions that are asked about that subject matter, with the knowledge that has been developed and is now basic to the area, and with the methods and standards by which claims to truth are judged.

Students must complete courses in topical groups in three major divisions (humanities, natural sciences and mathematics, and social sciences). For the B.A., three courses are required from each division, with no more than one course from any topical group. The B.G.S. requires two courses from each division, with no more than one from any topical group. To fulfill the requirement, a course must be designated as a principal course according to the codes listed below.

These are the major divisions, their topical subgroups, and the codes that identify them:

Humanities

  • HT: Historical studies
  • HL: Literature and the arts
  • HR: Philosophy and religion

Natural Sciences and Mathematics

  • NB: Biological sciences
  • NE: Earth sciences
  • NM: Mathematical sciences
  • NP: Physical science

Social Sciences

  • SC: Culture and society
  • SI: Individual behavior
  • SF: Public affairs

No course may fulfill both a principal course distribution requirement and a non-Western culture or second-level mathematics course requirement. Laboratory science courses designated as principal courses may fulfill both the laboratory science requirement and one of the distribution requirements. No free-standing laboratory course may by itself fulfill either the laboratory science requirement or a principal course requirement. Students should begin taking principal courses early in their academic careers. An honors equivalent of a principal course may fulfill a principal course requirement.

View all approved principal course distribution courses »

Non-Western Culture Requirement

A non-Western culture course acquaints students with the culture, society, and values of a non-Western people, for example, from Asia, the Pacific Islands, the Middle East, or Africa. Students must complete one approved non-Western culture course.

One approved non-Western culture course is required. Occasionally courses with varying topics fulfill the non-Western culture course requirement. See the Schedule of Classes for details. These courses are coded NW.

View all approved non-Western culture courses »

Transfer and Earned Credit Course Codes

These codes are used to evaluate transfer credit and to determine which academic requirements a course meets.

  • H: Humanities
  • N: Natural Sciences and Mathematics
  • S: Social Sciences
  • W: World Civilization and Culture
  • U: Undesignated Elective Credit (course does not satisfy distribution requirement)

All Pharmaceutical Chemistry courses

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This elective class will explore emerging areas of research currently impacting the pharmaceutical industry. Potential topics include; biologicals as therapeutics, drug targeting, prodrugs, nanotechnology, biological barriers, gene therapy, transporters, vaccines, intracellular drug trafficking, controlled release drug delivery, cancer therapy, analytical biotechnology and many others. The class will be team taught by PHCH faculty and guest speakers. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Must be accepted to the Pharmacy Program. LEC
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This elective class will explore emerging areas of research currently impacting the pharmaceutical industry. Potential topics include; biologicals as therapeutics, drug targeting, prodrugs, nanotechnology, biological barriers, gene therapy, transporters, vaccines, intracellular drug trafficking, controlled release drug delivery, cancer therapy, analytical biotechnology and many others. The class will be team taught by PHCH faculty and guest speakers. Prerequisite: Must be accepted to the Pharmacy Program. LEC
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This class will explore both the costs and time lines required for the approval of both new as well as generic drug products from identification of drug targets to FDA approval, and Phase 4 studies. Included will be a short history of the establishment of the FDA and its evolving role. The contributions of Frances Kelsey, the FDA scientist who fought the approval of thalidomide in the USA and thus saved many from the trauma of birth defects caused by the drug will be discussed. The class will be team taught by pharmaceutical chemistry faculty and guest speakers. Graded on a satisfactory/fail basis. Prerequisite: Completion of PHCH 626 or instructor permission. LEC
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This special topics course will cover the "public's perception" of drug discovery and development. This course is organized around a recently published book entitled "Drug Truths: Dispelling the Myths about Pharma R&D" (John Wiley & Sons, 2009). This book was written by John L. La Mattina, who was formally President of Pfizer Global Research ad Development. The course will address the following public myths about drug discovery and development: Cholesterol drugs are unnecessary, industry is more interested in "me-too" drugs than innovation, it takes industry too long to discover new drugs, drugs are discovered by academia, new medicines add cost but little benefit, big Pharma has failed and should learn from Biotech success, the industry invents diseases, new drugs are less safe than traditional medicine, industry spends more on advertising than R&D, and industry does not care about diseases of the developing world. Graded on a Satisfactory/Fail basis. Prerequisite: Must be accepted to the Pharmacy Program. LEC
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An introduction to the mathematics involved in filling prescriptions and in manufacturing pharmaceuticals. Includes an introduction to standard prescription notation and familiarization with pharmaceutical weights and measures. LEC
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Physical properties of pharmaceutical solutions and their physiological compatibility will be discussed (intermolecular interactions, energetics, colligative properties, isotonicity, pH, buffers and drug solubility). Kinetics and mechanisms of drug degradation in solution will also be introduced. Prerequisite: PHCH 517. LEC
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Vaccines are currently the most powerful therapeutic approach available for infectious disease and promise to become of increasing importance for a wide variety of other pathologies including cancer. This course discusses the immunological basis of vaccinology, types of vaccines currently available and in development and the process by which vaccines are made from the basic research stage through their pharmaceutical development and marketing. Ethical aspects of vaccine use will also be considered. Course graded on a satisfactory/fail basis. LEC
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A discussion of the basic concepts, and some clinical applications, of pharmacokinetics, clearance concepts, extravascular dosing, and the use of pharmacokinetics in dosage regimen design and adjustment. Prerequisite: PHCH 517 and PHCH 518. LEC
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A study of biological barriers to drug delivery, conventional dosage forms, and new and future drug delivery strategies. Prerequisite: PHCH 517, PHCH 518, and PHCH 625. LEC
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A lecture-discussion course concerned with identification of the contents of physiological fluids, changes in physiological fluid content induced by disease and drugs, and therapeutic drug monitoring: case study discussions and presentations are coordinated with the integrated laboratory. Prerequisite: Fifth-year standing and concomitant enrollment in integrated laboratory. LEC
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A study of selected topics of current interest which are pertinent to the area of pharmacy. This course is normally reserved as a didactic one that is offered occasionally when there is a special subject to be taught for one semester only. Prerequisite: Consent of instructor. IND
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Student will be assigned a suitable research project in the area of pharmaceutical analysis or pharmaceutics. Prerequisite: Consent of instructor. IND
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A student will be assigned a suitable research project in an area of pharmaceutical analysis or pharmaceutics. This course is offered regularly by the Department of Pharmaceutical Chemistry to meet the special needs of selected students, usually for one of the following two situations: (1) This course may be taken when a student has a special interest in a problem or area of limited scope and desires to pursue that study in depth under supervision of a member of the faculty. (2) This course is sometimes used as a remedial class to provide a mechanism of intensive review and study in an area of weakness. Prerequisite: Consent of instructor. IND
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Discussions, lectures, and laboratory work designed to acquaint and provide hands on experiences to advanced undergraduate and graduate students with experimental design, methods, and approaches relevant to modern research in pharmaceutical chemistry. Prerequisite: Consent of instructor. LEC
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First semester of a two-semester course. The course is designed to introduce the most important and basic concepts, methods, and tools used in Bioinformatics. Topics include (but not limited to) bioinformatics databases, sequence and structure alignment, protein structure prediction, protein folding, protein-protein interaction, Monte Carlo simulation, and molecular dynamics. Emphasis will be put on the understanding and utilization of these concepts and algorithms. The objective is to help the students to reach rapidly the frontier of bioinformatics and be able to use the bioinformatics tools to solve the problems on their own research. (Same as BINF 701.) LEC
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Second semester of a two-semester course in bioinformatics and computational biology. The course is designed to introduce the most important and basic concepts, methods, and tools used in Bioinformatics. Topics include (but not limited to) bioinformatics databases, sequence and structure alignment, protein structure prediction, protein folding, protein-protein interaction, Monte Carlo simulation, and molecular dynamics. Emphasis will be put on the understanding and utilization of these concepts and algorithms. The objective is to help the students to reach rapidly the frontier of bioinformatics and be able to use the bioinformatics tools to solve the problems on their own research. (Same as BINF 702.) LEC
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Communicating research proposals and experimental findings is a critical skill for scientists. Successful communication depends on clarity of thought and careful use of language. This course will use class discussions with examples and homework assignments to help prepare the graduate student to successfully communicate in both academia or industry settings. Graded on a satisfactory/unsatisfactory basis. Prerequisite: Must be accepted to the Pharmacy Program. LEC
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The course will survey the latest technology for delivering pharmaceuticals and biologicals to reduce side effects and enhance drug efficacy. The course will survey the latest research in this area and examine more classical delivery methods. A qualitative and quantitative understanding of drug delivery practice and theory is the goal. Prerequisite: Master's or PhD candidate in Engineering, Chemistry, Medicinal Chemistry, or Pharmaceutical Chemistry (by appointment for seniors or graduate students in departments not listed). LEC
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The course will survey the latest technology for delivering pharmaceuticals and biologicals to reduce side effects and enhance drug efficacy. The course will survey the latest research in this area and examine more classical delivery methods. A qualitative and quantitative understanding of drug delivery practice and theory is the goal. This course is only open to distance education students. Prerequisite: Master's candidate in Pharmaceutical Chemistry. LEC
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Physical properties of pharmaceutical solutions and their physiological compatibility will be discussed (intermolecular interactions, energetics, colligative properties, isotonicity, pH, buffers and drug solubility). Kinetics and mechanisms of drug degradation in solution will also be introduced. Prerequisite: Graduate standing. LEC
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Physical properties of pharmaceutical solutions and their physiological compatibility will be discussed (intermolecular interactions, energetics, colligative properties, isotonicity, pH, buffers and drug solubility). Kinetics and mechanisms of drug degradation in solution will also be introduced. This course is only open to distance education students. Prerequisite: Graduate standing. LEC
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A course on the use of the library as a research tool and the study of bibliographic techniques of literature searching. Emphasis on the literature of pharmaceutical chemistry and physical pharmacy. LEC
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Fundamental and advanced concepts in cell biology and the molecular interactions responsible for cell function, homeostasis and disease will be presented. Current analytical methods for examining cells and their molecular components will be discussed. Emphasis will be placed on the chemical and physical properties of individual proteins, nucleic acids and lipids and their assembly into cellular and subcellular structures. (Same as C&PE 725) LEC
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Fundamental and advanced concepts in cell biology and the molecular interactions responsible for cell function, homeostasis and disease will be presented. Current analytical methods for examining cells and their molecular components will be discussed. Emphasis will be placed on the chemical and physical properties of individual proteins, nucleic acids and lipids and their assembly into cellular and subcellular structures. This course is only open to distance education students. LEC
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A consideration of the structural features and driving forces that control the course of chemical reactions. Topics will include functional group chemistry: electronic structure, acid/base properties: molecular structure and properties (dipole, strain, and steric effects, inductive and resonance effects); dynamics of reactions (the major organic reaction mechanism, kinetics, energy profiles, isotope effects, linear free energy relationships), solvent effects, stereochemistry and conformation, an introduction to orbital symmetry control; basic thermodynamic and kinetic concepts; and an overview of important classes of mechanisms. This course is only open to distance education students. Prerequisite: CHEM 624 and CHEM 626. LEC
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An advanced course focusing on current and future strategies for targeted drug delivery to specific tissue sites. The emphasis of lectures and discussions is on routes of drug permeation across biological barriers; macromolecules, viruses, microparticulates, and cells as drug carriers; and prodrug delivery systems. Students are required to individually review selected topics. Prerequisite: Graduate standing or consent of the instructor. LEC
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A detailed study of the molecular aspects of nerve transmission will be covered with special emphasis on the uptake, storage, release, biosynthesis, and metabolism of specific neurotransmitters. Drugs affecting these processes and current research on receptor isolation and receptor mechanisms will be discussed from a chemical viewpoint. (Same as P&TX 775, BIOL 775, CHEM 775, MDCM 775 and NURO 775.) Prerequisite: BIOL 600 or equivalent. LEC
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Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientists in the laboratory, the scientist as author, grantee, reviewer, employer/employee, teacher/student, and citizen. Discussions will focus on case histories. Graded on a satisfactory/unsatisfactory basis. (Same as MDCM 801, NURO 801, P&TX 801 and PHCH 802.) LEC
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Lectures and discussion on ethical issues in the conduct of a scientific career, with emphasis on practical topics of special importance in molecular-level research in the chemical, biological, and pharmaceutical sciences. Topics will include the nature of ethics, the scientists in the laboratory, as author, grantee, reviewer, employer/employee, teacher/student, and citizen. Discussions will focus on case histories. Graded on a satisfactory/unsatisfactory basis. This course is only open to distance education students. (Same as PHCH 801, MDCM 801, NURO 801, and P&TX 801.) LEC
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The course will cover basic techniques of moral reasoning, especially as applied to ethical issues in the physical sciences and engineering. Topics covered will include the ethical conduct of research, the federal and professional guidelines for different kinds of research, and the ethical dimensions of publication and professional life. Emphasis will be on practical applications, cases and student involvement. (Same as GS 804, MDCM 804, NURO 804, and P&TX 804.) Prerequisite: Must be admitted to the program or division of Pharmacy to enroll in this class. LEC
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6This course is designed to provide an understanding of the formulation and stability of small and large drug candidates in the solid state. The first two-thirds of the course will focus on small molecules, with the last third being devoted to proteins. Prerequisite: Graduate standing in PHCH or consent of the instructor. LEC
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This course is designed to provide an understanding of the formulation and stability of small and large drug candidates in the solid state. The first two-thirds of the course will focus on small molecules, with the last third being devoted to proteins. This course is only open to distance education students. Prerequisite: Graduate standing in PHCH or consent of the instructor. Must be accepted to the Pharmacy Program. LEC
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A course on equilibria in aqueous and non-aqueous systems with emphasis on solutions of interest to pharmaceutical technology. Included are association-dissociation equilibria, complexation, protein binding calculation of species concentrations, estimation of solubility and ionization constants. Methods for the determination of chemical potential in solution are presented. LEC
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A course on equilibria in aqueous and non-aqueous systems with emphasis on solutions of interest to pharmaceutical technology. Included are association-dissociation equilibria, complexation, protein binding calculation of species concentrations, estimation of solubility and ionization constants. Methods for the determination of chemical potential in solution are presented. This course open only to distance education students. LEC
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Advanced course on pharmaceutical analysis. LEC
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This course is intended to be a comprehensive treatment of contemporary techniques used to validate analytical methods for the determination of drugs in the bulk form, pharmaceutical formulations, biological samples and other relevant media. The emphasis will be on chromatographic techniques reflecting the preeminent position that those techniques occupy in the field of pharmaceutical and biomedical analysis. Prerequisite: Previous or concurrent enrollment in PHCH 684. LEC
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A course on mass transport problems of pharmaceutical interest. Topics include physiological pharmacokinetic models, diffusive transport, and drug delivery systems. Prerequisite: MATH 320 or equivalent. LEC
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A course on mass transport problems of pharmaceutical interest. Topics include physiological pharmacokinetic models, diffusive transport, and drug delivery systems. This course is only open to distance education students. Prerequisite: MATH 320 or equivalent. LEC
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Advanced course on pharmaceutical analysis. This course is only open to distance education students. LEC
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A course designed to emphasize the important facets of recombinant proteins as pharmaceutical agents. Basics of protein structure and analysis will be introduced, and methods for production, isolation, and purification of recombinant proteins will be described. Potential chemical and physical degradation processes and strategies for circumventing these difficulties will be discussed. Prerequisite: BIOL 600 or consent of instructor. LEC
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A course designed to emphasize the important facets of recombinant proteins as pharmaceutical agents. Basics of protein structure and analysis will be introduced, and methods for production, isolation, and purification of recombinant proteins will be described. Potential chemical and physical degradation processes and strategies for circumventing these difficulties will be discussed. This course is only open to distance education students. Prerequisite: BIOL 600 or consent of instructor. LEC
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Advanced level research in collaboration with a faculty member in pharmaceutical chemistry or related areas. This course is limited to students who are doing research, but not necessarily working toward either a master's or a doctoral degree. RSH
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Master's Thesis. This course is only open to distance education students. THE
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Graded on a Satisfactory/Fail basis. THE
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This course provides the principles of kinetic data analysis as applied to problems in pharmaceutical chemistry. Topics include the setup and solution of rate equations related to chemical reactions; simplifications and approximations in complex equation systems; isotope, solvent and salt rate effects; and diffusion and activation controlled reactions. LEC
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This course provides the principles of kinetic data analysis as applied to problems in pharmaceutical chemistry. Topics include the setup and solution of rate equations related to chemical reactions; simplifications and approximations in complex equation systems; isotope, solvent and salt rate effects; and diffusion and activation controlled reactions. This course is only open to distance education students. LEC
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A course dealing with mechanisms and chemical kinetics of drug deterioration and stabilization. LEC
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A course dealing with mechanisms and chemical kinetics of drug deterioration and stabilization. This course is only open to distance education students. LEC
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Various topics pertinent to the area of pharmaceutical chemistry will be explored. Graded on a satisfactory/unsatisfactory basis. LEC
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A quantitative treatment of the processes involved with drug absorption, distribution, metabolism, and excretion in living systems. This course open only to distance education students. LEC
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A quantitative treatment of the processes involved with drug absorption, distribution, metabolism, and excretion in living systems. This course open only to on-campus students. LEC
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A course addressing special topics in biopharmaceutics and pharmacokinetics including complex modeling, treatment of data using computers, cell culture systems, and research topics. LEC
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A seminar on the chemistry of pharmaceutical systems. LEC
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A course addressing special topics in biopharmaceutics and pharmacokinetics including complex modeling, treatment of data using computers, cell culture systems, and research topics. This course is only open to distance education students. LEC
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Advanced level research in collaboration with a faculty member involving projects in pharmaceutical chemistry or related areas. Prerequisite: Doctoral degree or equivalent in an appropriate related area and consent of instructor. RSH
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