Roger A Rajewski, Ph.D., Director
Director
785 864-5158
Fax: 785 864-5097
rajewski@ku.edu
Dr. Rajewski has been involved in the Kansas Technology Enterprise Corporation-supported development of University of Kansas technologies for potential commercialization in the private sector for more than 10-years. He has supported the continued development and patent prosecution for the sulfobutyl ether cyclodextrin derivatives which have been patented by the University and licensed to CyDex, Inc., of Overland Park, KS. CyDex is commercializing this technology under the trade name "Captisol" for use as solubilizing and stabilizing agents in the formulation of GMP drug products.
During his tenure at KU he has helped guide the development of two additional technologies: drug processing with supercritical fluids and novel prodrug technologies. Multiple patents in both these areas have been or are being secured by the University to CritiTech, Inc., and the prodrug technologies have been licensed to ProQuest Pharmaceuticals, Inc., both of Lawrence, KS. Both of these companies are in the early stages of development and the technologies they have licensed are continuing to be advanced within the BIO Center. Dr. Rajewski has been involved in the incorporation of these companies, participated in reviewing the license arrangements, participated in making presentations to financing institutions and potential clients, contributed to the business plan development and multiple grant preparation activities, and identification of business and technical consultants. In addition, he provides technical input for many Kansas companies of which not all are directly associated with the University.
Michelle Kennedy, Ph.D.Dr. Kennedy has extensive experience in the contract pharmaceutical industry. She worked extensively with HPLC method development and validation as well as compendia methods for numerous drug substances and finished drug products. In her most recent position Dr. Kennedy was involved with the development, analysis and interpretation of a variety of pharmaceutical materials.
Mehmet Tanol, Ph.D.Dr. Tanol has extensive experience working independently on the organic synthesis of small molecules and peptide molecules. Dr. Tanol has more than twenty-years experience in an academic research environment. His expertise include synthesis of prodrugs (POM , Cyclic Peptides); total synthesis of potentially active heterocycles; stereoselective total synthesis of natural products with pharmacological activity; synthesis of new biodegradable transdermal penetration enhancers; .studies on physicochemical properties of synthesized compounds, leading to SAR and QSAR studies; preparation of the new enhancers and prodrugs for targeted drug delivery systems; and structure elucidation of unknown compounds using spectrometric methods.
John Haslam, Ph.D.
Research Associate
785 864-54847
Fax: 785 864-5097
jhaslam@ku.edu
Dr. Haslam has more than 40 years of industrial and academic research expereince. Dr. Haslam has extensive reserach expereince with the development of drug delivery systems including immediate and sustained release of tablets and capsules.
Karl Schorno, Ph.D.
Research Associate
785 864-5138
Fax: 785 864-5097
kschorno@ku.edu
Dr. Schorno. has over 30-years experience working in the pharmaceutical industry and in academic settings. More than 10 years of this experience has been focused on developing assays for drugs and their metabolites for pharmacokinetic analysis using LC/MS. Dr. Schorno has worked at Kansas City Analytical Services as the Analytical Director and then as the Director of Methods Developments. He also worked at Applied Analytical Industries for two years workign with analytical scientists in the development of LC/MS methods.
Joanna Krise
Research Associate
785 864-5138
Fax: 785 864-5097
jokrise@ku.edu
Jo Krise has more than 10-years of pharmaceutical research experince. Her expertise lies in the areas of pharmacokinetic studies of prodrugs and novel delivery formulations, as well as identification and quantification of proteins by nanoflow LC and quadrupole time of flight mass spectrometry.
Kathy Heppert
Senior Research Assistant
785 864-5138
Fax: 785 864-5097
kheppert@ku.edu
Kathy Heppert's area of expertise is in separation methods. She has 14-years of industrial experience, largely involved with development of separation methods for the analysis of drugs in biological matrices. Her expertise includes HPLC with UV, fluorescent and electrochemical detection and gas chromatography with FID, NDP, ECD and MS detection, and NMR and FTIR instrumentation.
Nancy Schwarting
Research Assistant
785 864-1523
Fax: 785 864-5097
nschwarting@ku.edu
Oznur Tanol
Research Aide
785 864-5138
Fax: 785 864-5097
otanol@ku.edu
