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Recent Publications by BIO Center affiliates

  • Burlison JA, Avila C, Vielhauer G, Lubbers DJ, Holzbeierlein J, Blagg BS., Development of novobiocin analogues that manifest anti-proliferative activity against several cancer cell lines. J Org Chem. 2008 Mar 21; 73(6): 2130-7. Epub 2008 Feb 23. PMID: 18293999
  • Tash JS, Chakrasali R, Jakkaraj SR, Hughes J, Smith SK, Hornbaker K, Heckert LL, Ozturk SB, Hadden MK, Kinzy TG, Blagg BS, Georg GI., Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and stimulates Il1a transcription in rat sertoli cells. Biol Reprod. 2008 Jun; 78(6): 1139-52. Epub 2008 Jan 23. PMID: 18218611
  • Roby KF, Niu F, Rajewski RA, Decedue C, Subramaniam B, Terranova PF., Syngeneic mouse model of epithelial ovarian cancer: effects of nanoparticulate paclitaxel, Nanotax. Adv Exp Med Biol. 2008; 622: 169-81. Review. PMID: 18546627
  • Shrestha A, Li R, Sil D, Pardeshi NN, Schwarting N, Schorno KS, Rajewski RA, Datta A, David SA., Pharmacokinetics of DS-96, an alkylpolyamine lipopolysaccharide sequestrant, in rodents. J Pharm Sci. 2008 Mar 27. PMID: 18383338
  • Zhang N, Chittasupho C, Duangrat C, Siahaan TJ, Berkland C., PLGA nanoparticle--peptide conjugate effectively targets intercellular cell-adhesion molecule-1. Bioconjug Chem. 2008 Jan; 19(1): 145-52. Epub 2007 Nov 13. PMID: 1799751
  • Shi L, Plumley CJ, Berkland C., Biodegradable nanoparticle flocculates for dry powder aerosol formulation. Langmuir. 2007 Oct 23; 23(22): 10897-901. Epub 2007 Sep 26. PMID: 17894513
  • Arnold MM, Gorman EM, Schieber LJ, Munson EJ, Berkland C., NanoCipro encapsulation in monodisperse large porous PLGA microparticles. J Control Release. 2007 Aug 16; 121(1-2): 100-9. Epub 2007 Jun 13. PMID: 1760487
  • Iskandarsyah, Tejo BA, Tambunan US, Verkhivker G, Siahaan TJ., Structural modifications of ICAM-1 cyclic peptides to improve the activity to inhibit heterotypic adhesion of T cells. Chem Biol Drug Des. 2008 Jul; 72(1): 27-33. Epub 2008 Jun 11. PMID: 18554252
  • Zheng K, Middaugh CR, Siahaan TJ., Evaluation of the physical stability of the EC5 domain of E-cadherin: Effects of pH, temperature, ionic strength, and disulfide bonds. J Pharm Sci. 2008 Apr 21. PMID: 1842879
  • Zimmerman T, Oyarzabal J, Sebastián ES, Majumdar S, Tejo BA, Siahaan TJ, Blanco FJ., ICAM-1 peptide inhibitors of T-cell adhesion bind to the allosteric site of LFA-1. An NMR characterization. Chem Biol Drug Des. 2007 Oct; 70(4): 347- 53. Epub 2007 Sep 14. PMID: 1786807
  • Yusuf-Makagiansar H, Yakovleva TV, Tejo BA, Jones K, Hu Y, Verkhivker GM, Audus KL, Siahaan TJ., Sequence recognition of alpha-LFA-1-derived peptides by ICAM-1 cell receptors: inhibitors of T-cell adhesion. Chem Biol Drug Des. 2007 Sep; 70(3) :237-46. PMID: 17718718
  • Murray JS, Oney S, Page JE, Kratochvil-Stava A, Hu Y, Makagiansar IT, Brown JC, Kobayashi N, Siahaan TJ., Suppression of type 1 diabetes in NOD mice by bifunctional peptide inhibitor: modulation of the immunological synapse formation. Chem Biol Drug Des. 2007 Sep; 70(3): 227-36. PMID: 17718717
  • Majumdar S, Kobayashi N, Krise JP, Siahaan TJ., Mechanism of internalization of an ICAM-1-derived peptide by human leukemic cell line HL-60: influence of physicochemical properties on targeted drug delivery. Mol Pharm. 2007 Sep-Oct; 4(5): 749-58. Epub 2007 Aug 7. PMID: 1768071
  • Kobayashi N, Kobayashi H, Gu L, Malefyt T, Siahaan TJ., Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor. J Pharmacol Exp Ther. 2007 Aug; 322(2) :879-86. Epub 2007 May 23. PMID: 17522343
  • Sharov VS, Dremina ES, Pennington J, Killmer J, Asmus C, Thorson M, Hong SJ, Li X, Stobaugh JF, Schöneich C., Selective fluorogenic derivatization of 3- nitrotyrosine and 3,4-dihydroxyphenylalanine in peptides: a method designed for quantitative proteomic analysis. Methods Enzymol. 2008;441:19-32. PMID: 18554527